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The development of mini- and micro-cultivation devices allows the optimization of bioprocesses to be speeded up, as well as a better understanding of microbia (…)

Authors: T. Ladner, A. Grünberger, C. Probst, D. Kohlheyer, J. Büchs, F. Delvigne

Journal: Bioprocesses, Bioreactors and Controls

Although the biocatalytic conversion of cellulosic biomass could replace fossil oil for the production of various compounds, it is often not economically vi (…)

Authors: Elena Antonov, Ivan Schlembach, Lars Regestein, Miriam A. Rosenbaum and Jochen Büchs

Journal: Biotechnology for Biofuels2017

Orbitally shaken cylindrical bioreactors [OrbShake bioreactors (OSRs)] without an impeller or sparger are increasingly being used for the suspension cultivation of mammalian c (…)

Authors: Zhu, Li-kuan; Monteil, Dominique T.; Shen, Xiao; Hacker, David L.; Song, Bo-yan; Wang, Zhen-long; De Jesus, Maria; Wurm, Florian M.

Journal: Biotechnology Progress (2016), early view online version

Microtiter plate (MTP) sealing tapes are commonly applied in bioprocess development and high throughput screening in order to maintain sterile conditions and avoid liquid evap (…)

Authors: Sieben, Michaela; Giese, Heiner; Grosch, Jan-Hendrik; Kauffmann, Kira; Büchs, Jochen

Journal: Biotechnology Journal (2016), early view

Quantitative evaluation of the shear threshold on C. tinctorius L. cell growth is vital for bioreactor system design and optimization of scaled-up industrial cultivation. The (…)

Authors: Liu, Yu; Wang, Ze-Jian; Zhang, JianWen; Xia, Jian-ye; Chu, Ju; Zhang, Si-Liang; Zhuang, Ying-Ping

Journal: Biochemical Engineering Journal /2016), Vol. 13, pp. 66-76

Because the model yeast Yarrowia lipolytica can synthesize and store lipids in quantities up to 20 % of its dry weight, it is a promising microorganism for oil production at a (…)

Authors: Back, Alexandre; Rossignol, Tristan; Krier, François; Nicaud, Jean-Marc: Dhulster, Pascal

Journal: Microbial Cell Factories (2016), Vol. 15, Issue 1, pp. 1-12

Orbitally shaken bioreactors (OSRs) support the suspension cultivation of animal cells at volumetric scales up to 200 L and are a potential alternative to stirred-tank bioreac (…)

Authors: Monteil, Dominique T.; Juvet, Valentin; Paz, Jonathan; Moniatte, Marc; Baldi, Lucia; Hacker, David L.; Wurm, Florian M.

Journal: Biotechnology Progress (2016)

Wave-mixed bioreactors have increasingly replaced stainless steel stirred tank reactors in seed inoculum productions and mammalian cell-based process developments. Pre-sterili (…)

Authors: Scholz, J.; Suppmann, S.

Journal: MethodsX (2016), Vol 3, pp. 497-501

Microalgae offer great potential for the industrial production of numerous compounds, but most of the currently available processes fail on economic aspects. Due to the lack o (…)

Authors: Morschett, Holger; Schiprowski, Danny; Mueller, Carsten; Mertens, Kolja; Felden, Pamela; Meyer, Joerg; Wiechert, Wolfgang; Oldiges, Marco

Journal: Biotechnology and Bioengineering (2016);

For strain improvement, robust and scalable high-throughput cultivation systems as well as simple and rapid high-throughput detection methods are crucial. However, most of the (…)

Authors: Lv, Xiangyun; Song, Jiali; Yu, Bo; Liu, Huilan; Li, Chao; Zhuang, Yingping; Wang, Yonghong

Journal: Bioprocess and Biosystems Engineering (2016), Vol. 39, Issue 11, pp. 1737-1747

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