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Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim (…)

Authors: Salehi-Nik, Nasim; Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Anisi, Fatemeh; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz

Journal: BioMed Research International (2013), Article Number: 762132

Several parameters such as mixing time, power consumption and deformation rates have been commonly reported in the literature for the hydrodynamic characterization of shaken f (…)

Authors: Palacios-Morales, C.; Aguayo-Vallejo, J. P.; Trujillo-Roldan, M. A.; Zenit, R.; Ascanio, G.; Cordova-Aguilar, M. S.

Journal: Chemical Engineering Science (2016), Volume: 152, Pages: 163-171

Orbitally shaken bioreactors, OSRs, are commonly employed in the pharmaceutical industry at the drug development and screening stage, because they provide a high throughput so (…)

Authors: Rodriguez, Gregorio; Micheletti, Martina; Ducci, Andrea

Journal: Chemical Engineering Research and Design (2018)

The mixing dynamics in a cylindrical shaken bioreactor are investigated by means of velocity and kinetic energy and mixing time measurements obtained with phase-resolved PIV a (…)

Authors: Rodriguez, G.;Weheliye, W.; Anderlei, T.; Micheletti, M.; Yianneskis, M.; Ducci, A.

Journal: Chemical Engineering Research and Design (2013), Volume 91, Issue 11

Phase-resolved particle image velocimetry measurements were carried out to assess the flow dynamics occurring in orbitally shaken bioreactors of cylindrical geometry when work (…)

Authors: Ducci, Andrea; Weheliye, Weheliye Hashi

Journal: Aiche Journal (2014), Volume: 60; Issue: 11; Pages: 3951-3968

Weissella cibaria RBA12 produced a maximum of 9 mg/ml dextran (with 90% efficiency) using shake flask culture under the optimized concentration of medium components viz. 2% (w (…)

Authors: Baruah, Rwivoo; Deka, Barsha; Kashyap, Niharika; Goyal, Arun

Journal: Applied Biochemistry and Biotechnology (2018), Volume: 184, Issue: 1, Pages: 1-11

Microtiter plates (MTP) are often applied as culture vessels in high-throughput screening programs. If online measuring techniques are available, MTPs can al (…)

Authors: Ladner, Tobias; Held, Markus; Flitsch, David; Beckers, Mario; Büchs, Jochen

Journal: Microbial Cell Factories, Volume: 15, Article Number: 206

Coccoliths are plates of CaCO3 produced from coccolithophorid microalgae cells. The coccolithophorid species Emiliana huxleyi has been intensively studied for being the most a (…)

Authors: Jakob, Ioanna; Weggenmann, Fabiola; Posten, Clemens

Journal: Algal Research (April 2018), Volume 31, Pages 47-59

Orbitally shaken bioreactors (OSRs) are commonly used for the cultivation of mammalian cells in suspension. Here we conducted a three-dimensional computational fluid dynamics (…)

Authors: Zhu, Likuan, Monteil, Dominique T.; Wang, Yukui; Song, Boyan; Hacker, David L.; Wurm, Maria J.; Li, Xiaobin; Wang, Zhenlong; Wurm, Florian M.

Journal: Biochemical Engineering Journal (2018), Volume: 129, Pages: 84-95

Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation th (…)

Authors: Flitsch, David; Krabbe, Sebastian; Ladner, Tobias; Beckers, Mario; Schilling, Jana; Mahr, Stefan; Conrath, Uwe; Schomburg, Werner K; Büchs, Jochen

Journal: Journal of Biological Engineering (2016), Volume: 10, Article Number: 14

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