Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim (…)
Authors: Salehi-Nik, Nasim; Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Anisi, Fatemeh; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz
Journal: BioMed Research International (2013), Article Number: 762132
Several parameters such as mixing time, power consumption and deformation rates have been commonly reported in the literature for the hydrodynamic characterization of shaken f (…)
Authors: Palacios-Morales, C.; Aguayo-Vallejo, J. P.; Trujillo-Roldan, M. A.; Zenit, R.; Ascanio, G.; Cordova-Aguilar, M. S.
Journal: Chemical Engineering Science (2016), Volume: 152, Pages: 163-171
Orbitally shaken bioreactors, OSRs, are commonly employed in the pharmaceutical industry at the drug development and screening stage, because they provide a high throughput so (…)
Authors: Rodriguez, Gregorio; Micheletti, Martina; Ducci, Andrea
Journal: Chemical Engineering Research and Design (2018)
The mixing dynamics in a cylindrical shaken bioreactor are investigated by means of velocity and kinetic energy and mixing time measurements obtained with phase-resolved PIV a (…)
Authors: Rodriguez, G.;Weheliye, W.; Anderlei, T.; Micheletti, M.; Yianneskis, M.; Ducci, A.
Journal: Chemical Engineering Research and Design (2013), Volume 91, Issue 11
Phase-resolved particle image velocimetry measurements were carried out to assess the flow dynamics occurring in orbitally shaken bioreactors of cylindrical geometry when work (…)
Authors: Ducci, Andrea; Weheliye, Weheliye Hashi
Journal: Aiche Journal (2014), Volume: 60; Issue: 11; Pages: 3951-3968
Weissella cibaria RBA12 produced a maximum of 9 mg/ml dextran (with 90% efficiency) using shake flask culture under the optimized concentration of medium components viz. 2% (w (…)
Authors: Baruah, Rwivoo; Deka, Barsha; Kashyap, Niharika; Goyal, Arun
Journal: Applied Biochemistry and Biotechnology (2018), Volume: 184, Issue: 1, Pages: 1-11
Microtiter plates (MTP) are often applied as culture vessels in high-throughput screening programs. If online measuring techniques are available, MTPs can al (…)
Authors: Ladner, Tobias; Held, Markus; Flitsch, David; Beckers, Mario; Büchs, Jochen
Journal: Microbial Cell Factories, Volume: 15, Article Number: 206
Coccoliths are plates of CaCO3 produced from coccolithophorid microalgae cells. The coccolithophorid species Emiliana huxleyi has been intensively studied for being the most a (…)
Authors: Jakob, Ioanna; Weggenmann, Fabiola; Posten, Clemens
Journal: Algal Research (April 2018), Volume 31, Pages 47-59
Orbitally shaken bioreactors (OSRs) are commonly used for the cultivation of mammalian cells in suspension. Here we conducted a three-dimensional computational fluid dynamics (…)
Authors: Zhu, Likuan, Monteil, Dominique T.; Wang, Yukui; Song, Boyan; Hacker, David L.; Wurm, Maria J.; Li, Xiaobin; Wang, Zhenlong; Wurm, Florian M.
Journal: Biochemical Engineering Journal (2018), Volume: 129, Pages: 84-95
Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation th (…)
Authors: Flitsch, David; Krabbe, Sebastian; Ladner, Tobias; Beckers, Mario; Schilling, Jana; Mahr, Stefan; Conrath, Uwe; Schomburg, Werner K; Büchs, Jochen
Journal: Journal of Biological Engineering (2016), Volume: 10, Article Number: 14
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